The Redwire Space Advanced Space Experiment Processor (ADSEP) is a fully automated, multi-use single middeck locker processing facility used to conduct a variety of life and physical-science research and small-batch production. The ADSEP facility contains three independent thermal zones, each accommodating one “mini-laboratory” cassette, and an internal computer that controls the processing of all three cassettes. Each cassette housing is designed to provide up to 2-levels of containment for each experiment, which allows for experiments that are an HRL-2. The facility is agnostic to the content of the cassettes. Therefore, completely independent studies can be run in different cassettes simultaneously. The cassettes are “hot swappable”, enabling crews to successfully run disparate experiments back-to-back.